Liver cancer
Liver cancer starts when cells in the liver begin to grow in an uncontrolled way. Many liver cancers begin in the liver itself. This is called primary liver cancer. The most common type is hepatocellular carcinoma (HCC).1
Primary liver cancer is different from cancer that spreads to the liver from somewhere else in the body. When cancer spreads, it is called metastatic cancer.1
What are the types of liver cancer?
Types of primary liver cancer include:¹
What are the common symptoms of liver cancer?
Liver cancer may not cause symptoms early on. As it grows, some people may notice:2, 3
- Pain on the right side of the stomach
- Unexplained weight loss
- Loss of appetite
- Feeling full after eating a small amount
- Nausea and vomiting
- Swelling of the stomach (ascites)
- Yellowing of the skin or eyes (jaundice)
- Fatigue and weakness
These symptoms can also happen with other conditions. If your symptoms don’t stop, or get worse, your doctor may recommend tests.
How is liver cancer diagnosed?
If a provider suspects liver cancer, several tests may help confirm the disease:4
- Blood tests: These may include liver function tests (LFTs) and alpha-fetoprotein (AFP) tests
- Imaging tests: Ultrasound, CT scans or MRI scans help show tumors or changes in the liver
- Biopsy: A tissue sample may be taken to confirm the exact type of cancer
A provider will also look at your health history, any risks you may have and the symptoms you feel.
What are the treatment options for liver cancer?
Treatment depends on the type of liver cancer, how far it is, and how healthy the person is. Common approaches include:5
- Closely watching: If the tumor is smaller than 1 centimeter, it is monitored with check-ups every 3 months
- Surgery: Removing the part of the liver where cancer is found
- Liver transplant: Replacing a liver with a healthy donor liver
- Ablation therapies: Destroy cancer cells using heat, cold or alcohol
- Embolization: Blocks blood flow to the tumor
- Targeted therapy: Medications that attack cancer cells
- Immunotherapy: Medicines that help the immune system attack cancer cells
- Radiation: Targeted radiation may help shrink tumors